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The use of antibiotics for the treatment of pertussis has changed over time. In the mid-1930s, penicillin was used in the treatment of pertussis, and was the first effective treatment for pertussis. However, the drug's side effects made it unpopular, and it was quickly replaced by other antibiotics. In the mid-1970s, erythromycin became the first treatment for pertussis that was effective against all strains of the bacterium. However, the drug is not effective against all strains of bacteria causing pertussis. In the mid-1980s, erythromycin was replaced by a newer drug, erythromycin estolate, which is still used today.

B. pertussis-specific immune globulin, another vaccine given to adults and children who are unvaccinated or have had only one dose of the vaccine, is the best way to protect from infection. Unfortunately, this vaccine is more expensive than the DTaP vaccine.

Whooping cough can be life-threatening in infants younger than 1 year and in older children and adults who have not been vaccinated or have not received the minimum number of doses. Symptoms include:

Coughing that lasts for more than 14 days.

Coughing that causes excessive phlegm.

Rapid breathing.

Loss of consciousness.

Patients with cancer all require adequate protection from radiation exposure. Although the outcomes are generally good for patients with cancer, there is a need to balance the side effects of radiation with their benefits. The risk of radiation-induced malignancy has been difficult to estimate, and there are still gaps in the knowledge of its pathogenesis and manifestation. There is an increase in morbidity and mortality for patients with cancer when the radiation dose is higher, and it has been reported that a 2.5 mrem increase in the dose leads to a 0.21% increase in the risk of death for patients with cancer. In addition, the cancer risk increases in a linear dose-response fashion with a doubling in the radiation exposure from 0.1 to 2.5 mrem per year [30,31,32,33].

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